Pflugerville Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it attempts to restore itself to normal before the harm was done. Pflugerville Wellness Center is always amazed at how the body takes care of itself! Pflugerville Wellness Center sees its Pflugerville chiropractic care as a partner of the body’s system in healing particularly when spine pain is an issue. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is proving value in its ability to interrupt the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are linked to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to the cellular level via autophagy, the natural process via which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin boosted autophagy and decreased the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin prevents intervertebral disc degeneration by stimulating autophagy. (3) Wow. Pflugerville Wellness Center is inspired by this research to see just how well melatonin can work for Pflugerville back pain linked to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is a very common condition seen at Pflugerville Wellness Center that positive news of melatonin’s benefits are quite rousing. A new study described that melatonin could modulate the extracellular matrix of the disc remodeling process initiated by IL-1 β. Additionally, melatonin decreased the inflammatory cell collection and decreased the release of linked inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin disrupted the IL-1B feedback loop, researchers postulated that melatonin may contribute to the healing process of intervertebral discs after damage has already been done. (1) Pflugerville Wellness Center will keep following the new research regarding the role inflammation has in Pflugerville disc degeneration and melatonin’s role in reducing it.

INFLAMMATION AND MELATONIN

The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is increasing. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other mechanisms is quite appropriate. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland produces melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) activities. (1) Melatonin’s specific influence on inflammation and disc degeneration is most attention-getting to Pflugerville Wellness Center and our Pflugerville back pain patients.

CONTACT Pflugerville Wellness Center

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Pflugerville chiropractic appointment with Pflugerville Wellness Center now. We can discuss how inflammation affects your back pain and how melatonin may help with the related disc degeneration.

 
Pflugerville Wellness Center shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."